Data resources are essential for the long-term preservation of scientific data and reproducibility of science. The SIB Swiss Institute of Bioinformatics has the mission to provide the life science community with a stable and sustainable data infrastructure. The Institute manages a portfolio of databases and software tools, which vary from manually curated knowledge bases such as UniProtKB/Swiss-Prot, neXtProt, and Bgee, to online tools such as SWISS-MODEL and SwissDrugDesign. SIB aims to ensure that these SIB resources are available long-term, i.e. as long as their scientific return-on-investment and impact are high. SIB's vision is that data and research results should be freely accessible to all. For this reason, the institute promotes the adoption of open licenses. The presentation and paper will describe the processes that support the identification, evaluation, and development of SIB Resources. For over 10 years, SIB employs a set of indicators that reflect the multiple and complex facets of data resources. These indicators set quality standards that guide and inform both the SIB Scientific Advisory Board in its evaluation, and the managers of the databases and tools in the development of their respective resources towards scientific excellence and Open Science. Continuous monitoring of usage trends and scientific impact of the SIB resources provide information to support their life cycle management. A professional management framework with central services such as a user experience & knowledge sharing team and a license advisory committee support the promotion of excellence in resource development and operation.